Figure 6

Bioluminescence and fluorescence imaging of mice with a spinal implant infection 72 h post 1D9-680 probe injection. At 72 h PI of the 1D9-680 probe, co-localization of the probe in 8 mice with infected implants is evidenced by bioluminescence and fluorescence imaging as described for Fig. 3. As expected, neither bioluminescence nor fluorescence are detectable in the 4 control mice with sterile spinal implants.