Figure 7

Bioluminescence and fluorescence imaging of mice with a spinal allograft infection 72 h post 1D9-680 probe injection. At 72 h PI of the 1D9-680 probe, co-localization of the probe in 4 mice with infected dorsally placed cancellous human allograft implants is evidenced by bioluminescence and fluorescence imaging as described for Fig. 3. As expected, neither bioluminescence nor fluorescence are detectable in the 3 control mice with sterile allograft implants.