Figure 6 | Scientific Reports

Figure 6

From: SARS-CoV-2 receptor ACE2 is co-expressed with genes related to transmembrane serine proteases, viral entry, immunity and cellular stress

Figure 6

Protein interaction network of genes most significantly (Bonferoni-adjusted p < 1E−11) correlated and anti-correlated genes with ACE2 shows IFI16 (r = 0.8719), LIMA1 (r = 0.8955), CNNM3 (r = − 0.8732), HNF4A (r = − 0.8750), TRAF3IP2 (r = 0.8816), ASB2 (r = 0.8791) and FANCC (r = − 0.8682) as hub genes. Genes found as interactors in the BioGrid database are marked in red, the original geneset of ACE2-correlated genes is marked in green, hub genes and ACE2 have yellow shading.

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