Figure 7

Overexpression of the epigenetically regulated miRNAs affects the expression of predicted downstream targets. qPCR showing variation in expression of miRNAs’ target genes in response to the indicated miRNAs overexpression of (A) miRNA-204-3p, (B) miRNA-3652, and (C) miRNA-4286 in KF-Tx. (D) qPCR showing diffrencial expression of the same miRNAs’ target genes in A2780 cells and A2780-Tx cells. The results are means ± SE from independent triplicates (*p < 0.05, **p < 0.01 and ***p < 0.001) as obtained from ANOVA.