Figure 3 | Scientific Reports

Figure 3

From: Fused isoselenazolium salts suppress breast cancer cell growth by dramatic increase in pyruvate-dependent mitochondrial ROS production

Figure 3

The concentration-dependent effects of compounds 3 and 6 on mitochondrial function in permeabilized 4T1 cells. Concentration dependent changes in mitochondrial respiration rate (A) and H2O2 production rate (B) and H2O2/O ratio (C) at Complex I or II linked OXPHOS. P—pyruvate; M—malate; G—glutamate. Values are shown as mean ± S.D. (n = 3–5 experiments) relative to baseline (dashed line)—before addition of the compound.

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