Table 4 Time varying cox analysis of hypertension stages for major adverse cardiovascular events according to both age and sex groups.

From: Age and sex specific target of blood pressure for the prevention of cardiovascular event among the treatment naive hypertensive patients

Group

40–49

50–59

60–69

70+

HR

95% CI

HR

95% CI

HR

95% CI

HR

95% CI

Male

Normal BP

Reference

 

Reference

 

Reference

 

Reference

 

Elevate BP

1.13

(0.93–1.38)

1.02

(0.82–1.28)

1.02

(0.79–1.3)

0.68

(0.42–1.11)

Stage 1 HTN

1.30

(1.14–1.48)

1.11

(0.95–1.29)

1.19

(1.00–1.41)

1.00

(0.74–1.34)

Stage 2 HTN

1.97

(1.70–2.29)

1.74

(1.48–2.05)

1.39

(1.15–1.66)

1.50

(1.12–2.00)

Female

Normal BP

Reference

 

Reference

 

Reference

 

Reference

 

Elevate BP

1.09

(0.79–1.49)

1.30

(0.98–1.73)

0.98

(0.71–1.35)

1.14

(0.70–1.87)

Stage 1 HTN

1.20

(0.96–1.50)

1.21

(0.98–1.51)

1.37

(1.10–1.71)

1.54

(1.10–2.16)

Stage 2 HTN

1.59

(1.18–2.15)

1.25

(0.95–1.64)

1.65

(1.31–2.09)

1.63

(1.16–2.31)

  1. The models was used with adjusting age, BMI, total cholesterol, fasting glucose, smoking status, drinking habit, CCI and calendar year.
  2. HTN hypertension, BP blood pressure, BMI body mass index, CCI Charlson comorbidity index, HR hazard ratio, CI confidence interval.