Figure 6 | Scientific Reports

Figure 6

From: Non-invasive assessment of skeletal muscle fibrosis in mice using nuclear magnetic resonance imaging and ultrasound shear wave elastography

Figure 6

Increased stiffness in fibrotic skeletal muscle. (a) Boxplots showing that ankle plantar flexion increases the shear-wave modulus in both injured and control muscles, from C57BL/6 and DBA/2J mice, but no difference between injured and control muscles could be detected (Supplementary Table S4). (b) The viscoelastic index was higher in injured muscles and (c) correlated with collagen fraction, indicating that muscle stiffness is increased in fibrotic muscles and that it can be detected non-invasively with SWE. Lines connect injured and control muscles for each mouse in (b). (c) Scatter plot with fitted linear regression and 95% confidence interval in grey.

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