Table 2 Multivariate analysis for predicting factors of low HDL-C.

From: Prognostic effect of high-density lipoprotein cholesterol level in patients with atherosclerotic cardiovascular disease under statin treatment

Parameter

Hazard ratio

95% CI

p value

Age

0.99

0.98–1.00

 < 0.01

Male (vs. female)

0.52

0.44–0.62

 < 0.0001

History hypertension

1.05

0.90–1.23

0.52

History of diabetes mellitus

1.54

1.33–1.77

 < 0.0001

History of heart failure

1.08

0.88–1.34

0.46

History of myocardial infarction

1.33

1.10–1.60

 < 0.01

Previous coronary/peripheral intervention

1.12

0.97–1.30

0.13

History of ischemic stroke/TIA

0.97

0.77–1.22

0.78

Cigarette smoking history

1.23

1.05–1.44

0.01

Statin intensity (vs. moderate intensity)

Low intensity

0.94

0.78–1.14

0.55

High intensity

0.87

0.64–1.18

0.37

Anti-platelets therapy

0.98

0.77–1.26

0.90

ARB/ACEI

0.97

0.84–1.11

0.62

Beta-blocker

1.35

1.18–1.56

 < 0.0001

BMI (vs. BMI ≥ 27.5 )

BMI < 23

0.49

0.40–0.61

 < 0.0001

23 ≤ BMI < 27.5

0.74

0.64–0.87

0.0001

eGFR (vs. eGFR > 60 ml/min/1.73m2)

30 < eGFR ≤ 60

1.01

0.85–1.20

0.92

eGFR ≤ 30

1.58

1.01–2.50

0.05

  1. *Abbreviations are the same as the Table 1. eGFR, estimated glomerular filtration rate.
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