Figure 2 | Scientific Reports

Figure 2

From: Genome-wide correlation analysis to identify amplitude regulators of circadian transcriptome output

Figure 2

A positive correlation between the percentage of cycling transcripts and the mean level of Rorc. (A) The peak phase of core clock gene expression in CT (Circadian Time) determined by MetaCycle. (B) The relative amplitudes of core clock gene expression determined by MetaCycle. (C) Correlation between % rhythmic transcripts and the mean levels of each core clock gene determined by MetaCycle. (D) Correlation between % rhythmic transcripts and the mean levels of Per2AS in each tissue. Each color corresponds to a tissue; liver (purple), kidney (light purple), lung (blue), brown adipose (light blue), heart (green), adrenal (light green), aorta (yellow), cerebellum (gold), hypothalamus (orange), muscle (coral), white adipose (red), brainstem (dark red). Core clock gene expression that did not fulfill Benjamini–Hochberg q < 0.05 criteria for rhythmicity was not included. (E) Single value decomposition (SVD) of tissues (left) or core clock genes (right). Eigentissues and eigengenes 1 and 2 were projected onto clock gene expression values, Rorc indicated in red.

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