Figure 2 | Scientific Reports

Figure 2

From: An update to the Monro–Kellie doctrine to reflect tissue compliance after severe ischemic and hemorrhagic stroke

Figure 2

In experiment 1, neuron soma volume (a, c, e, g) and density (b, d, f, h) were analyzed with unbiased stereology on days 1, 3, and 7 following striatal ICH or sham operation. Astrocyte soma volume was also analyzed on day 1. Areas assessed in all animals included in CA1 (a, b, i), CA3 (c, d), S1 (e, f), and contralateral striatum (g, h, j). Ipsilateral striatum was not assessed as it was largely destroyed by the ICH, as expected. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 versus respective SHAM controls. Scatterplots were made using GraphPad Prism version 8.4.3 for macOS, GraphPad Software, San Diego, California USA, www.graphpad.com.

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