Figure 4

The effect of maternal progesterone on pituitary gene expression in male fetuses at d75 gestation compared to vehicle controls. Maternal progesterone administration decreased expression of GNRHR, FSHB and LHB in fetal males (C = 10; P = 7). Box plot whiskers are lowest and highest observed values, box is the upper and lower quartile, with median represented by line in box. Unpaired, two-tailed Student’s t test was used for comparing means of two treatment groups with equal variances accepting P < 0.05 as significant (*P < 0.05, **P < 0.01).