Figure 6 | Scientific Reports

Figure 6

From: A combined 3D printing/CNC micro-milling method to fabricate a large-scale microfluidic device with the small size 3D architectures: an application for tumor spheroid production

Figure 6

Steps to produce the master mold and casting with PDMS. (a, b) Two CNC milled parts are bonded to each other permanently using a solvent bonding method. (c) The 3D printed mold is assembled on the CNC mold and fixed with reusable putty adhesive. (d) The cover and microwell PDMS layers bonded together using the plasma bonding method to produce the microwell chip. (e, f) The optical micrographs of PDMS layers with the variable and constant depth (300 µm) microwells.

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