Table 2 The laboratory findings for all the patients and the subgroup divided by family cluster.

Blood test

 White blood cell, E + 09/L

4.73 (3.90–5.45)

4.20 (3.69–5.05)

5.37 (4.54–6.06)

0.092

  < 4

11 (29.73%)

8 (38.10%)

3 (18.75%)

0.202

  ≥ 4, < 10

26 (70.27%)

13 (61.90%)

13 (81.25%)

 Lymphocyte, E + 09/L

1.70 (1.20–2.00)

1.40 (1.00–2.10)

1.80 (1.70–2.00)

0.748

  ≥ 0, < 4

34 (91.89%)

19 (90.48%)

15 (93.75%)

0.718

  ≥ 4, < 8

3 (8.11%)

2 (9.52%)

1 (6.25%)

 Neutrophils, E + 09/L

2.60 (2.00–3.20)

2.60 (2.00–2.90)

2.95 (2.10–3.82)

0.139

  < 2

9 (24.32%)

5 (23.81%)

4 (25.00%)

0.238

  ≥ 2, < 7

26 (70.27%)

16 (76.19%)

10 (62.50%)

  ≥ 7

2 (5.41%)

0 (0.00%)

2 (12.50%)

 Platelet, E + 09/L

188.00 (158.00–238.00)

165.00 (149.00–205.00)

228.00 (183.75–238.75)

0.194

  < 100

1 (2.70%)

1 (4.76%)

0 (0.00%)

0.623

  ≥ 100, < 300

33 (89.19%)

18 (85.71%)

15 (93.75%)

  ≥ 300

3 (8.11%)

2 (9.52%)

1 (6.25%)

Liver function

 Alanine aminotransferase (U/L)

25.22 (24.01) 18.00 (14.00–27.00)

20.00 (15.00–27.00)

16.50 (13.00–36.25)

0.69

  < 40

34 (91.89%)

20 (95.24%)

14 (87.50%)

0.393

  ≥ 40

3 (8.11%)

1 (4.76%)

2 (12.50%)

 Aspartate aminotransferase (U/L)

25.86 (14.34) 23.00 (19.00–28.00)

23.00 (19.00–27.00)

22.50 (18.75–28.75)

0.527

  < 40

34 (91.89%)

19 (90.48%)

15 (93.75%)

0.718

  ≥ 40

3 (8.11%)

2 (9.52%)

1 (6.25%)

Cardiac function

 Lactate dehydrogenase (U/L)

212.00 (180.00–275.00)

227.00 (189.00–275.00)

202.00 (154.00–256.75)

0.458

  < 245

25 (67.57%)

13 (61.90%)

12 (75.00%)

0.399

  ≥ 245

12 (32.43%)

8 (38.10%)

4 (25.00%)

 Creatine kinase (U/L)

97.98 (71.12) 84.10 (51.40–106.90)

88.00 (72.10–153.70)

57.40 (45.90–94.88)

0.657

  < 140

29 (78.38%)

15 (71.43%)

14 (87.50%)

0.239

  ≥ 140

8 (21.62%)

6 (28.57%)

2 (12.50%)

 Creatine kinase isoenzymes (U/L)

14.00 (12.00–22.00)

16.00 (13.00–24.00)

13.50 (11.75–17.00)

0.494

  < 25

31 (83.78%)

16 (76.19%)

15 (93.75%)

0.151

  ≥ 25

6 (16.22%)

5 (23.81%)

1 (6.25%)

 Myoglobin (U/L)

15.00 (10.00–25.00)

17.00 (13.00–29.00)

12.50 (8.75–16.25)

0.08

  < 46

33 (89.19%)

18 (85.71%)

15 (93.75%)

0.435

   46

4 (10.81%)

3 (14.29%)

1 (6.25%)

 Type B natriuretic peptide (pg/mL)

45.00 (31.00–103.00)

65.00 (45.00–116.00)

31.00 (19.00–50.75)

0.206

  < 125

29 (78.38%)

16 (76.19%)

13 (81.25%)

0.711

  ≥ 125

8 (21.62%)

5 (23.81%)

3 (18.75%)

Inflammatory factors

 Erythrocyte sedimentation rate (mm/h)

15.78 (18.06) 10.00 (3.00–20.00)

14.90 (19.44) 7.00 (4.00–20.00)

16.94 (16.63) 14.50 (2.00–21.25)

0.74

  < 20

27 (72.97%)

15 (71.43%)

12 (75.00%)

0.809

  ≥ 20

10 (27.03%)

6 (28.57%)

4 (25.00%)

 Interlekin 6 (pg/mL)

12.36 (10.23) 9.01 (3.11–19.84)

13.39 (10.67) 10.56 (3.45–19.93)

11.02 (9.78) 7.34 (2.66–19.13)

0.492

   < 7

16 (43.24%)

8 (38.10%)

8 (50.00%)

0.469

  ≥ 7

21 (56.76%)

13 (61.90%)

8 (50.00%)

 Procalcitonin (ng/mL)

0.05 (0.03) 0.04 (0.03–0.05)

0.04 (0.02) 0.04 (0.03–0.05)

0.05 (0.04) 0.04 (0.02–0.07)

0.135

  < 0.05

26 (70.27%)

16 (76.19%)

10 (62.50%)

0.367

  ≥ 0.05

11 (29.73%)

5 (23.81%)

6 (37.50%)

 C-reactive protein (mg/L)

12.51 (21.53) 3.31 (0.56–12.00)

3.20 (0.27–10.20)

3.67 (0.63–14.05)

0.214

  < 8.2

24 (64.86%)

15 (71.43%)

9 (56.25%)

0.338

  ≥ 8.2

13 (35.14%)

6 (28.57%)

7 (43.75%)

 Ferritin (U/L)

122.50 (74.20–345.40)

87.63 (62.61–325.80)

200.95 (92.53–456.07)

0.043

  < 400

30 (81.08%)

19 (90.48%)

11 (68.75%)

0.095

  ≥ 400

7 (18.92%)

2 (9.52%)

5 (31.25%)