Table 3 Renal survival of ADTKD-UMOD patients classified by UMOD domain or cysteine substitution.

From: Autosomal dominant tubulointerstitial kidney disease genotype and phenotype correlation in a Chinese cohort

(A) Domain

EGF

D8C

ZP

Total

N

6

3

2

11

Male/female

4/2

0/3

1/1

5/6

Prognosis ESRD (age)

3 (40,52,20)

1 (26)

1 (25)

5

Slowly progression(age)

3 (24,41,44)

2 (26,45)

1 (27)

5

B

Cysteine

Others

Total

 

N

5

6

11

 

Male/female

1/4

4/2

5/6

 

Diagnosis age

29 ± 11

33 ± 13

31 ± 12

 

Prognosis ESRD (age)

0

5 (20,25,26,40,52)

5

 

Slowly progression (age)

5 (24,26,27,41,45)

1 (49)

6

 
  1. ADTKD autosomal dominant tubulointerstitial kidney disease, NOS not otherwise specified, ESRD end stage renal disease, EGF epidermal growth factor, ZP zona pellucida.
  2. A. Renal survival of ADTKD-UMOD patients classified by UMOD domain. The prognosis was analyzed by Kaplan–Meier analysis, with p > 0.05. B. Renal survival for ADTKD-UMOD patients classified by cysteine substitution. Diagnosis age did not statistically differ between the two groups. (p = 0.632) The prognosis was analyzed by Kaplan–Meier analysis, with P = 0.015. ESRD end stage renal disease.
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