Table 4 Clinical features of the patients with ADTKD and ADTKD-NOS.
Character | ADTKD (genetically confirmed) | ADTKD-NOS (clinically confirmed) | P value |
|---|---|---|---|
Number | 13 | 5 | |
Male/Female | 6/7 | 2/3 | 1.000 |
Age of diagnosis | 31.5 ± 10.8 | 26 ± 7.5 | 0.318 |
Creatinine (μmol/L) | 213.1 ± 91.6 | 177.9 ± 40 | 0.426 |
Uric acid (μmol/L) | 531.6 ± 153.6 | 493.7 ± 156 | 0.645 |
Blood Urea Nitrogen (mmol/L) | 8.8 ± 6.1 | 6.4 ± 3.8 | 0.425 |
24-h urinary protein (g) | 0.19 ± 0.21 | 0.47 ± 0.56 | 0.328 |
With/without Proteinuria (No.) | 2/11 | 1/5 | 0.099 |
Gout | 4 | 1 | 1.000 |
Hypertension | 6 | 0 | 0.114 |
Renal cyst | 38.5% | 40% | 1.000 |
Family history | 76.9% | 100% | 0.522 |
Renal biopsy | 4 | 5 | |
Tubulointerstitial-nephropathy | 4 | 3 | |
Medullary cystic kidney disease | 0 | 2 | |
Cystic dilation of tubules/acute tubular injury | 0 | 0 | |
Number of patients with genetic variation | 13 | 0 |
