Table 1 Demographics and lung functions derived from the PFTs and QCTs of COPD and non-COPD subjects.
From: A 3D-CNN model with CT-based parametric response mapping for classifying COPD subjects
Non-COPD subjects (n = 392) | COPD subjects (n = 204) | P value | |
|---|---|---|---|
Demographics | |||
Male/females, n (%) | 190/202 (48.5%/51.5%) | 173/31 (84.8%/15.2%) | < 0.001 |
Age, years | 55.9 (16.3) | 72.9 (7.4) | < 0.001 |
Height, cm | 161.3 (10.2) | 161.3 (7.5) | 0.992 |
Weight, kg | 63.2 (12.0) | 59.8 (9.8) | < 0.001 |
Never/former/current smokers, n (%) | 262/54/76 (66.8%/13.8%/19.4%) | 50/53/101 (24.5%/26.0%/49.5%) | < 0.001 |
COPD stages (I, II, III, IV), n (%) | 0 | 88/87/27/2 (43.1%/42.7%/13.2%/1.0%) | |
PFT-based lung functions | |||
FEV1, %predicted | 100.0 (14.1) | 75.0(20.0) | < 0.001 |
FVC, %predicted | 98.2 (13.6) | 93.1(20.0) | < 0.001 |
FEV1/FVC × 100 | 80.4 (6.0) | 58.9 (8.0) | < 0.001 |
QCT-based lung functions | |||
TLC, litre | 4.7 (1.3) | 4.3 (1.0) | < 0.001 |
FRC, litre | 3.0 (1.0) | 2.8 (0.9) | 0.005 |
Emph% | 1.7 (2.5) | 8.5 (7.5) | < 0.001 |
fSAD% | 11.2 (13.4) | 23.7 (13.6) | < 0.001 |
ADI | 0.4 (0.1) | 0.3 (0.1) | 0.074 |
SRI | 0.5 (0.03) | 0.6 (0.03) | < 0.001 |
J | 1.7 (0.4) | 1.5 (0.3) | < 0.001 |
