Table 2 Coefficients and P-values for multiple linear regression between a quadratic polynomial in age and mean myelin water fraction (MWF), and between a quadratic polynomial in age and mean geometric mean T2 of intra- and extra-cellular water (IET2), for each region of interest.

From: An atlas for human brain myelin content throughout the adult life span

Region of Interest

MWF

IET2

Adjusted r-value

P-value (Age)

P-Value (Age2)

Adjusted r-value

P-value (Age)

P-Value (Age2)

Genu of corpus callosum

0.184

0.024

0.029

0.640

0.317

0.022

Body of corpus callosum

0.408

0.010

0.051

0.453

0.263

0.056

Splenium of corpus callosum

0.346

0.032

0.106

0.263

0.819

0.475

Cerebral peduncle

0.467

6.14E−05*

5.19E−04*

0.394

7.17E−03

0.035

Anterior limb of internal capsule

0.459

7.78E−05*

6.54E−04*

0.486

1.92E−07*

1.69E−07*

Posterior limb of internal capsule

0.463

1.08E−04*

9.11E−04*

0.421

5.16E−04*

1.01E−04*

Retrolenticular part of internal capsule

0.371

2.30E−03

9.59E−03

0.298

3.87E−03

1.94E−03

Anterior corona radiata

0.327

1.54E−03

0.041

0.628

3.81E−03

7.44E−05*

Superior corona radiata

0.348

7.99E−04*

2.38E−03

0.548

0.015

8.84E−04*

Posterior corona radiata

0.323

2.12E−03

5.75E−03

0.402

0.030

5.81E−03

Posterior thalamic radiation

0.163

0.068

0.048

0.530

0.040

3.22E−03

Sagittal stratum

0.258

4.62E−03

7.20E−03

0.351

0.185

0.058

External capsules

0.423

3.69E−04*

2.21E−03

0.423

1.75E−05*

7.74E−06*

Cingulum (cingulate gyrus)

0.369

2.21E−04*

6.35E−04*

0.318

0.015

5.08E−03

Fornix (cres) / Stria terminalis

0.441

3.00E−04*

2.12E−03

0.178

0.112

0.068

Superior longitudinal fasciculus

0.338

7.31E−04*

1.88E−03

0.475

0.438

0.103

All white matter ROIs

0.389

5.34E−04*

2.34E−03

0.499

0.015

1.34E−03

White matter mask

0.464

2.09E−05*

1.53E−04*

0.401

5.19E−04*

1.28E−04*

Gray matter mask

0.448

1.49E−03

0.011

0.755

1.01E−10*

1.09E−07*

  1. Statistically significant linear (age) and quadratic (age2) contributions to the regression model are bold for P < 0.01 and bold* for P < 0.001.
Back to article page