Table 2 Correlation analysis between mutated genes and the origin of tumor samples.
From: A comprehensive analysis of somatic alterations in Chinese ovarian cancer patients
Genes | Primary lesions (49) | Metastatic lesions (10) | P-value (Fisher’s exact) | ||
---|---|---|---|---|---|
Number of mutations | Mutational frequency (%) | Number of mutations | Mutational frequency (%) | ||
TP53 | 45 | 91.84 | 8 | 80.00 | 0.266433 |
LRP2 | 1 | 2.04 | 2 | 20.00 | 0.07152 |
NTRK3 | 1 | 2.04 | 2 | 20.00 | 0.07152 |
TERT | 7 | 14.29 | 0 | 0.00 | 0.590097 |
PRKCI | 6 | 12.24 | 0 | 0.00 | 0.576789 |
EZH2 | 5 | 10.20 | 0 | 0.00 | 0.576789 |
FAM135B | 5 | 10.20 | 0 | 0.00 | 0.576789 |
FGF12 | 5 | 10.20 | 0 | 0.00 | 0.576789 |
NOTCH1 | 5 | 10.20 | 0 | 0.00 | 0.576789 |
PTK2 | 5 | 10.20 | 0 | 0.00 | 0.576789 |
SDHA | 5 | 10.20 | 0 | 0.00 | 0.576789 |
VEGFA | 5 | 10.20 | 0 | 0.00 | 0.576789 |
BRCA1 | 4 | 8.16 | 0 | 0.00 | 0.805958 |