Table 3 Analysis of patients with severe steatosis.

From: Microbiota analysis and transient elastography reveal new extra-hepatic components of liver steatosis and fibrosis in obese patients

 

Low steatosis (LS)

N = 13

Severe steatosis (HS)

N = 36

p value

p value

Logistic regression analysis

Clinical parameters

Age (years)

49.2

50.1

0.79

 

Weight (kg)

98.1

108.1

0.06

 

BMI (kg/m2)

34.3

36.5

0.16

 

Waist (cm)

112.0

116.9

0.18

 

Waist to hip ratio

0.95

0.980

0.07

 

Sex (M/F)

3/10

22/14

0.02

0.231

Antidiabetic drug (n/total)

3/13

11/36

0.61

 

Biological results

ASAT (UI/L)

21.0

28.6

0.02

 

ALAT (UI/L)

28.1

45.3

0.006

0.068

γGT (UI/L)

40.0

50.6

0.29

 

Fasting glycemia (mg/dL)

95.1

109.2

0.01

0.091

Bioimpedance analysis

Resistance

480.5

440.1

0.15

 

Fat free mass (kg)

62.4

68.4

0.19

 

Total body fat (kg)

37.9

39.6

0.68

 

CT-scan data

Subcutaneous fat area (cm2)

340.4

363.1

0.62

 

Visceral fat area (cm2)

197.3

275.4

0.007

0.567

Whole muscle area (cm2)

155.4

182.4

0.07

 

Skeletal muscle index (cm2/m2)

53.3

61.9

0.04

0.040

Skeletal muscle density (HU)

32.2

33.1

0.67

 

Skeletal muscle density index (HU/cm2)

0.216

0.186

0.06

 
  1. Results are given as mean value (and compared with a bilateral Student-t-test). Number of patients are compared with a chi-squared test. All significant parameters from the univariate analysis (except for collinear values) included in the logistic regression analysis are reported in the last column.
  2. ASAT aspartate aminotransferase, ALAT alanine aminotransferase, BMI body mass index, γGT γ-glutamyl transferase, HU Hounsfield unit.
  3. Significant differences are presented in bold.
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