Figure 4 | Scientific Reports

Figure 4

From: Respiratory chain components are required for peptidoglycan recognition protein-induced thiol depletion and killing in Bacillus subtilis and Escherichia coli

Figure 4

B. subtilis ΔglpD and Δaro mutants have attenuated PGLYRP4-induced depletion of thiols (a), exogenous menaquinone (MK) increases PGLYRP4-induced depletion of thiols in these mutants (b), and MK synthesis inhibitor DPA attenuates PGLYRP4-induced depletion of thiols, which is restored by addition of exogenous MK (c). The results are the amounts of thiols expressed as percent of control with BSA (100%) and are means ± SEM from 4 to 6 experiments (biological replicates). B. subtilis 6633 was used in (c). ^P < 0.05, ^^P < 0.001 mutant vs parental strain; NS not significant (P > 0.05); *P < 0.05, **P < 0.001 as indicated by brackets.

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