Table 3 The adjusted risks for rapid eGFR decline (eGFR decline more than 3 ml/min/1.73 m2/year) within 1 year prior to questionnaire examination in study patients according to self-care behavior and disease knowledge scores.

From: The interaction between self-care behavior and disease knowledge on the decline in renal function in chronic kidney disease

 

eGFR slope

Proportion of eGFR decline more than 3 ml/min/1.73 m2/year

Rapid eGFR decline

p-value

ml/min/1.73 m2/year

Adjusted odds ratio (95% Cl)

Self-care behavior (per score)

− 1.7 (-4.0, 1.4)

147/454 (32.4)

0.97 (0.95–0.98)

0.002

Self-care behavior (quartiles)

Quartile 1

− 2.4 (− 4.8, 1.3)

53/125 (42.4)

Reference

 

Quartile 2

− 1.4 (− 4.2, 2.0)

37/107 (34.6)

0.73 (0.42–1.27)

0.3

Quartile 3

− 1.7 (− 3.4, 1.1)

35/126 (27.8)

0.55 (0.33–0.99)

0.04

Quartile 4

− 1.8 (− 2.9, 0.6)

22/96 (22.9)

0.38 (0.21–0.71)

0.002

Disease knowledge (per score)

− 1.7 (− 4.0, 1.4)

147/454 (32.4)

0.91 (0.87–0.95)

 < 0.001

Disease knowledge (quartiles)

Quartile 1

− 2.2 (− 5.3, 1.2)

59/138 (42.82)

Reference

 

Quartile 2

− 2.1 (− 4.1, 1.4)

32/90 (35.6)

0.73 (0.41–1.31)

0.3

Quartile 3

− 1.5 (− 3.2, 0.9)

33/120 (27.5)

0.46 (0.26–0.80)

0.006

Quartile 4

− 1.5 (− 2.8, 2.3)

23/106 (21.7)

0.29 (0.15–0.54)

 < 0.001

Low self-care score and low disease knowledge score

− 2.4 (− 5.0, 1.6)

58/133 (43.6)

Reference

 

High self-care score and low disease knowledge score

− 2.1 (− 4.3, 1.2)

33/95 (34.7)

0.78 (0.44–1.38)

0.4

Low self-care score and high disease knowledge score

− 1.4 (− 4.0, 2.4)

32/99 (32.3)

0.58 (0.32–1.04)

0.07

High self-care score and high disease knowledge score

− 1.5 (− 2.7, 0.8)

24/127 (18.9)

0.28 (0.16–0.50)

 < 0.001

  1. Adjusted for age, sex and all variables in Table 1 whose p-value were < 0.05 including diabetes mellitus, hemoglobin, baseline estimated glomerular filtration rate, and log-formed urine protein-creatinine ratio in unadjusted model.
  2. Self-care score quartile cut at 59, 67 and 72.
  3. Disease knowledge score quartile cut at 18, 22 and 25.
  4. Low self-care as less than median of self-care score; high self-care as above median of self-care score.
  5. Low disease knowledge as less than median of disease knowledge score; high disease knowledge as above median of disease knowledge score.
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