Table 1 Modifications of metrics of echocardiography and SCG/BCG according to the dose of dobutamine infusion.
Parameters | Baseline | 5 µg/kg/min | 10 µg/kg/min | 20 µg/kg/min | PAll |
---|---|---|---|---|---|
Sex (% male) | 47.1 | – | – | – | |
Age | 25 ± 1.7 | – | – | – | |
BMI | 22.5 ± 2.1 | – | – | – | |
SV | 61.2 ± 12.0 | 71.8 ± 13.0 | 82.5 ± 19.0 | 84.7 ± 18.0 | 0.0001 |
CO | 4.1 ± 0.8 | 4.7 ± 0.8 | 6.4 ± 1.0 | 8.8 ± 1.9 | 0.0001 |
LVOT Vmax | 20.2 ± 2.6 | 24.3 ± 3.3 | 27.7 ± 2.8 | 28.1 ± 3.3 | 0.0001 |
LVOT VTI | 0.98 ± 0.13 | 1.26 ± 0.24 | 1.72 ± 0.22 | 1.85 ± 0.25 | 0.0001 |
HR | 70.6 ± 10.3 | 72.4 ± 10.4 | 87.3 ± 16.5 | 115.2 ± 21.6 | 0.0001 |
LVEF | 63.3 ± 4.5 | 69.2 ± 8.5 | 78.9 ± 4.7 | 81.7 ± 4.0 | 0.0001 |
SCG | |||||
\({D}_{Max}^{Lin}\) | 0.15 ± 0.08 | 0.22 ± 0.10 | 0.23 ± 0.08 | 0.19 ± 0.08 | 0.003 |
\({\mathrm{D}}_{\mathrm{max}}^{\mathrm{Rot}}\) | 11.7 ± 8.6 | 21.1 ± 16.5 | 24.9 ± 12.2 | 23.3 ± 11.9 | 0.0001 |
\({V}_{Max}^{Lin}\) | 1.69 ± 0.7 | 2.87 ± 1.13 | 3.54 ± 1.14 | 3.62 ± 1.30 | 0.0001 |
\({V}_{Max}^{Rot}\) | 244.0 ± 150.9 | 527.5 ± 356.8 | 746.2 ± 426.2 | 816.6 ± 512.0 | 0.0001 |
\({\mathrm{iK}}_{\mathrm{Lin}}\) | 40.0 ± 30.0 | 80.0 ± 50.0 | 120.0 ± 60.0 | 110.0 ± 70.0 | 0.0001 |
\({\mathrm{iK}}_{\mathrm{Rot}}\) | 20.0 ± 20.0 | 60.0 ± 60.0 | 90.0 ± 80.0 | 100.0 ± 90.0 | 0.0001 |
\({P}_{Max}^{Lin}\) | 11.5 ± 1.4 | 13.8 ± 1.8 | 15.4 ± 1.6 | 15.8 ± 1.9 | 0.0001 |
\({P}_{Max}^{Rot}\) | 0.009 ± 0.009 | 0.08 ± 0.05 | 0.47 ± 0.45 | 0.18 ± 0.06 | 0.0001 |
BCG | |||||
\({D}_{Max}^{Lin}\) | 0.05 ± 0.02 | 0.06 ± 0.02 | 0.06 ± 0.02 | 0.07 ± 0.03 | 0.002 |
\({D}_{Max}^{Rot}\) | 2.1 ± 1.1 | 2.9 ± 1.1 | 3.6 ± 1.3 | 4.3 ± 1.6 | 0.0001 |
\({V}_{Max}^{Lin}\) | 0.5 ± 0.2 | 0.7 ± 0.2 | 0.8 ± 0.3 | 1.0 ± 0.3 | 0.0001 |
\({V}_{Max}^{Rot}\) | 49.0 ± 31.7 | 95.5 ± 62.5 | 124.7 ± 82.8 | 147.7 ± 86.7 | 0.0001 |
\({\mathrm{iK}}_{\mathrm{Lin}}\) | 6.0 ± 4.0 | 8.0 ± 4.0 | 10.0 ± 5.0 | 10.0 ± 7.0 | 0.0001 |
\({\mathrm{iK}}_{\mathrm{Rot}}\) | 0.7 ± 0.7 | 2.0 ± 0.8 | 3.0 ± 2.0 | 4.0 ± 3.0 | 0.0001 |
\({\mathrm{P}}_{\mathrm{max}}^{\mathrm{Lin}}\) | 0.3e−3 ± 0.0e−3 | 0.7e−3 ± 0.0002 | 0.7e−3 ± 0.4e−3 | 1.0e−3 ± 0.3e−3 | 0.0001 |
\({\mathrm{P}}_{\mathrm{max}}^{\mathrm{Rot}}\) | 0.04e−3 ± 0.0e−3 | 0.3e−3 ± 0.03e−3 | 0.3e−3 ± 0.04e−3 | 0.7e−3 ± 0.09e−3 | 0.0001 |