Table 1 Demographic characteristics of IMPROVE and UKB participants.
IMPROVE | UKB1 | UKB2 | |
|---|---|---|---|
Nmax | 3300 | 2202 | 20,182 |
Male (%) | 1695 (51.4) | 1042 (47.3) | 9759 (48.4) |
Baseline | |||
Age (years) | 64.2 (5.4) | 55.7 (7.6) | 55.2 (7.5) |
Weight (kg) | 76.7 (15.1) | 76.1 (14.5) | 76.9 (14.8) |
Waist (cm) | 94 (13) | 88 (12) | 88 (13) |
Hip (cm) | 102 (10) | 102 (8) | 102 (8) |
WHR | 0.92 (0.09) | 0.86 (0.09) | 0.86 (0.09) |
BMI (kg/m2) | 27.3 (4.2) | 26.4 (3.9) | 26.6 (4.2) |
SBP (mmHg) | 142 (18) | 136 (18) | 136 (18) |
DBP (mmHg) | 82 (10) | 82 (10) | 82 (10) |
SBP* (mmHg) | 151 (21) | 138 (19) | 138 (19) |
DBP* (mmHg) | 88 (11) | 83 (11) | 83 (11) |
T2D | 880 (26.7) | 46 (2.1) | 45 (2.2) |
HTN | 2634 (79.8) | 974 (45.0) | 8765 (45.2) |
HTN medication | 1904 (57.7) | 332 (15.2) | 2820 (14.0) |
Lipid-lowering medication | 1623 (49.2) | 172 (18.4) | 1677 (18.9) |
ISH | 0 (0) | 21 (1.0) | 259 (1.3) |
IMTmean (mm) | 0.891 (0.199) | na | na |
IMTmax (mm) | 2.037 (0.813) | na | na |
Current smoking | 498 (15.1) | 139 (6.3) | 1234 (6.1) |
Former smoking | 1216 (36.9) | 746 (33.9) | 6656 (33.0) |
Follow-up | |||
Age | 66.7 (5.4) | 61.8 (7.5) | 63.2 (7.5) |
Weight | na | 75.6 (14.6) | 76.3 (15.0) |
Waist | na | 86 (12) | 88 (12) |
Hip | na | 100 (8) | 101 (9) |
WHR | na | 0.86 (0.08) | 0.87 (0.09) |
BMI | na | 26.4 (4.0) | 26.5 (4.4) |
SBP | na | 138 (20) | 137 (18) |
DBP | na | 83 (11) | 79 (10) |
SBP* | na | 140 (20) | 141 (20) |
DBP* | na | 81 (11) | 81 (11) |
T2D | na | 79 (3.6) | 867 (4.3) |
HTN | na | 1121 (51.5) | 12,414 (62.0) |
HTN medication | na | 466 (21.2) | 4568 (22.7) |
Lipid-lowering medication | na | 408 (22.3) | 4557 (26.4) |
ISH | 119 (3.6) | 43 (2.0) | 333 (1.7) |
IMTmean (mm) | na | 0.672 (0.119) | 0.682 (0.125) |
IMTmax (mm) | na | 0.888 (0.182) | 0.914 (0.297) |
Progression of IMTmean | 0.0186 (0.032) | na | na |
Progression of IMTmax | 0.0439 (0.163) | na | na |
Current smoking | na | 99 (4.6) | 708 (3.5) |
Former smoker | na | 742 (34.1) | 6800 (33.9) |
MHQ | |||
Nmax (% of group) | na | 1528 (69.4) | 10,079 (49.9) |
BD | na | 28 (1.8) | 196 (1.4) |
MDD | na | 410 (29.9) | 3512 (28.6) |
