Figure 1 | Scientific Reports

Figure 1

From: Outer membrane vesicles containing OmpA induce mitochondrial fragmentation to promote pathogenesis of Acinetobacter baumannii

Figure 1

OmpAAb is required for bacterial colonization and dissemination in vivo. (A) Schematic representation of the mouse infection (created with BioRender.com). (B–E) Neutropenic BALB/c mice were infected intranasally with 107 colony forming units (CFUs) of the indicated bacteria. Each group included five mice per time point. Two- and 24-h post-infection, animals were euthanized and lungs, liver, kidneys and spleen were homogenized and CFUs were plated from these organs. Blue dashed line in (B) represents the CFU with which each mouse was infected with. Black dotted line in (C–E) represents the limit of detection. Shown is the representative data from two independent experiments. Two-tailed p value using Mann–Whitney test *p \(\le \) 0.05, **p \(\le \) 0.01.

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