Table 3 Comparison of cerebral MRI findings between the age subgroups of < 50 years, 50–60 years, 60–70 years, and ≥ 70 years.
< 50 years (n = 44) | 50–60 years (n = 43) | 60–70 years (n = 59) | ≥ 70 years (n = 126) | P value | |
|---|---|---|---|---|---|
Male sex, n (%) | 22 (50%) | 26 (60%) | 47 (80%) | 74 (59%) | 0.011a |
Comorbidity | |||||
Hypertension, n (%) | 8 (18%) | 20 (47%) | 35 (59%) | 100 (79%) | < 0.001a |
Diabetes mellitus, n (%) | 4 (9%) | 7 (16%) | 11 (19%) | 32 (25%) | 0.110a |
Dyslipidemia, n (%) | 10 (23%) | 8 (19%) | 23 (39%) | 38 (30%) | 0.110a |
Obesity, n (%) | 12 (27%) | 15 (35%) | 17 (29%) | 27 (21%) | 0.334a |
Smoking, n (%) | |||||
Current smoker | 13 (30%) | 8 (19%) | 9 (15%) | 13 (10%) | 0.165b |
Ex-smoker | 2 (5%) | 8 (19%) | 13 (22%) | 22 (17%) | |
Never | 29 (66%) | 27 (63%) | 37 (63%) | 91 (72%) | |
Coronary artery disease, n (%) | 4 (9%) | 3 (7%) | 8 (14%) | 25 (20%) | 0.118a |
Valvular heart disease or Atrial fibrillation, n (%) | 9 (20%) | 8 (19%) | 7 (12%) | 22 (17%) | 0.665a |
History of stroke or TIA, n (%) | 1 (2%) | 3 (7%) | 6 (10%) | 17 (13%) | 0.165a |
Brain MRI | |||||
Diffusion weighted image, n (%) | 39 (89%) | 39 (91%) | 48 (81%) | 118 (94%) | |
Co-incident cerebral infarction, n (%) | 3 (8%) | 5 (13%) | 8 (17%) | 33 (30%) | 0.021a |
Cerebral small vessel disease, n (%) | 11 (25%) | 31 (72%) | 43 (73%) | 113 (90%) | < 0.001a |
White matter hyperintensity, n (%) | 7 (16%) | 31 (72%) | 41 (69%) | 109 (87%) | < 0.001a |
Grade 1 | 7 (16%) | 28 (65%) | 32 (54%) | 61 (48%) | < 0.001b |
Grade 2 | 0 (0%) | 2 (5%) | 8 (14%) | 39 (31%) | |
Grade 3 | 0 (0%) | 1 (2%) | 1 (2%) | 9 (7%) | |
Cerebral microbleeds, n (%) | 3 (7%) | 8 (19%) | 9 (15%) | 18 (14%) | 0.481 |
Silent lacunar infarct, n (%) | 3 (7%) | 11 (26%) | 21 (36%) | 47 (37%) | 0.002a |
MRA—ICA involvement, n (%) | 10 (23%) | 16 (34%) | 28 (47%) | 84 (67%) | < 0.001a |
Mild stenosis | 4 (9%) | 9 (21%) | 18 (31%) | 46 (37%) | < 0.001b |
Moderate to severe stenosis | 6 (14%) | 7 (16%) | 10 (17%) | 38 (30%) | |
