Table 2 Meta-analysis for the effect of B. monnieri on memory and attention in healthy people.

From: The effectiveness of Bacopa monnieri (Linn.) Wettst. as a nootropic, neuroprotective, or antidepressant supplement: analysis of the available clinical data

Outcomes

n Studies

n Individuals

Outcome differences

Heterogeneity

Publication bias-fail safe N

Reference

Weighted mean (95% CI)

P value

I2 (%)

P value

Rosenthal (P value)

AVLT delayed recall

4

239

0.85 (− 0.22, 1.91)

0.120

93.08

 < 0.01

29 (< 0.001)

74,76,77,80

AVLT learning rate

4

237

0.50 (− 0.17, 1.16)

0.142

83.53

 < 0.01

13 (< 0.001)

72,76,77,80

AVLT forgetting rate

3

193

− 0.03 (− 0.31, 0.27)

0.851

0

0.453

0 (0.371)

72,77,80

AVLT proactive interference

3

193

0.62 (− 0.05, 1.29)

0.071

80.41

0.006

15 (< 0.001)

72,77,80

AVLT retroactive interference

3

193

− 1.3 (− 0.57, 0.31)

0.565

57.17

0.097

0 (0.180)

72,77,80

Digit span forwards

5

245

0.07 (− 0.80, 0.91)

0.873

90.28

 < 0.01

0 (0.335)

4,73,76,81

Digit span reverse

5

245

− 0.04

0.095

78.19

0.001

0 (0.393)

4,72,73,76,81

Paired associate learning

3

123

0.31 (− 0.10, 0.72)

0.143

19.9

0.287

1 (0.048)

73,76,81

Simple reaction time

4

212

− 0.07 (− 0.36, 0.22)

0.618

0

0.564

0 (0.310)

72,75,79,81

Choice reaction time

4

212

− 0.20 (− 0.50, 0.09)

0.179

9

0.518

0 (0.082)

72,75,79,81

Logical memory

3

162

1.11 (0.43, 1.80)

0.001

73.23

0.024

43 (0.001)

73,78,81