Figure 4

The relationship between the expression of hub genes and clinical characteristics. (A) mRNA levels of the 14 hub genes. The colour of each point represents the log2FC, and the size represents the P-value. (B) The association between the 14 hub genes and overall survival, as determined by univariate Cox regression analysis. The colour represents the hazard ratio (HR), and the size represents the P-value. (C) Summary of the mutations in the 14 hub genes in urogenital cancers via cBioPortal website (http://www.cbioportal.org/). Each row represents a gene, and each column represents a tumour sample. Red bars indicate gene amplifications, blue bars represent deep deletions, green squares indicate missense mutations, and grey bars indicate truncation mutations. (D) The relationship between the expression of the 14 hub genes and the clinical characteristics of bladder cancer. The numbers in rectangles indicate the correlation coefficient and the numbers in brackets indicate the P-value.