Table 1 Functional roles of 14 hub genes.
No | Genes | Full name | Function |
|---|---|---|---|
1 | ORM1 | Orosomucoid 1 | Innate immune system and carvedilol pathway, pharmacokinetics |
2 | ORM2 | Orosomucoid 2 | Innate immune system and response to elevated platelet cytosolic Ca2 + |
3 | NEUROG3 | Neurogenin 3 | DNA-binding transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding |
4 | INSM1 | Insulinoma-associated 1 | Regulation of beta-cell development and developmental biology |
5 | MYBPH | Myosin binding protein H | G13 signaling pathway and actin nucleation by ARP-WASP complex |
6 | TRIM63 | Tripartite Motif Containing 63 | Ligase activity and obsolete signal transducer activity |
7 | MYLPF | Myosin, light chain 11, regulatory | Calcium ion binding and structural constituent of muscle |
8 | MYH6 | Myosin heavy chain 6 | Sertoli-sertoli cell junction dynamics and translocation of GLUT4 to the plasma membrane |
9 | CSRP3 | Cysteine and glycine rich protein 3 | Structural constituent of muscle and telethonin binding |
10 | MYH7 | Myosin heavy chain 7 | Sertoli-sertoli cell junction dynamics and translocation of GLUT4 to the plasma membrane |
11 | TCAP | Titin-Cap | Ion channel binding and structural constituent of muscle |
12 | TNNT3 | Troponin T3, fast skeletal type | Actin binding and tropomyosin binding |
13 | MYH7B | Myosin heavy chain 7B | Myosin heavy chain 7B |
14 | HP | Haptoglobin | Serine-type endopeptidase activity and hemoglobin binding |
