Table 3 Effect of timepoint and outcome.

From: Serum fibroblast growth factor 21 levels after out of hospital cardiac arrest are associated with neurological outcome

Fixed effects on FGF 21 concentration (n = 112)

df

F

P-value

Timepoint

3

5.6

 < 0.01*

Poor outcome

1

6.1

0.01*

Timepoint × Poor outcome

3

3.0

0.03*

Pairwise comparisons

Mean difference

95% CI

P-value

Timepoint

 24 h–admission

− 0.12

− 0.81–0.58

0.74

 48 h–24 h

0.83

0.42–1.2

 < 0.001*

 72 h–48 h

− 0.07

− 0.92–0.79

0.88

Poor outcome

 Poor–good outcome

1.2

0.24–2.2

0.01*

Timepoint × Poor outcome

 Admission

 Poor–good outcome

0.68

− 0.58–1.9

0.29

 24 h

 Poor–good outcome

0.36

− 0.61–1.3

0.46

 48 h

 Poor–good outcome

1.4

0.002–2.8

0.05

 72 h

 Poor–good outcome

2.5

0.62–4.4

 < 0.01**

  1. Good outcome, 6-month Cerebral Performance Categories (CPC) 1–2; Poor outcome, 6-month CPC 3–5; df, numerator degrees of freedom; CI, confidence interval.
  2. *Statistically significant at the P < 0.05 level (Fixed effects and interactions).
  3. **Statistically significant at the P < 0.0125 level (four pairwise comparisons of interactions).