Table 3 Effect of timepoint and outcome.
Fixed effects on FGF 21 concentration (n = 112) | df | F | P-value |
---|---|---|---|
Timepoint | 3 | 5.6 | < 0.01* |
Poor outcome | 1 | 6.1 | 0.01* |
Timepoint × Poor outcome | 3 | 3.0 | 0.03* |
Pairwise comparisons | Mean difference | 95% CI | P-value |
---|---|---|---|
Timepoint | |||
24 h–admission | − 0.12 | − 0.81–0.58 | 0.74 |
48 h–24 h | 0.83 | 0.42–1.2 | < 0.001* |
72 h–48 h | − 0.07 | − 0.92–0.79 | 0.88 |
Poor outcome | |||
Poor–good outcome | 1.2 | 0.24–2.2 | 0.01* |
Timepoint × Poor outcome | |||
Admission Poor–good outcome | 0.68 | − 0.58–1.9 | 0.29 |
24 h Poor–good outcome | 0.36 | − 0.61–1.3 | 0.46 |
48 h Poor–good outcome | 1.4 | 0.002–2.8 | 0.05 |
72 h Poor–good outcome | 2.5 | 0.62–4.4 | < 0.01** |