Figure 7
Consistent detection of ESIONPs after injection. All maps were zero-filled from 160 × 160 × 160 µm3 to 80 × 80 × 80 µm3. Each panel represents for individual mouse, total 15 mice. (a–e) |ΔR1| maps after injection of 1 µl of saline in 5 individual mice. (f–j) |ΔR1| maps after injection of 1 µl of ESIONPs at 0.1 mM iron concentration in 5 additional mice. (k–o) |ΔR1| maps after injection of 1 µl of ESIONPs at 0.25 mM iron concentration in 5 additional mice. The box in panel (k) indicates the region of interest used for quantitative analysis. Note that small amounts of signal change ipsilateral to injection indicated by arrow can be detected, likely due to variability in injection technique.
