Table 3 Insula gray matter volume in relation to alcohol/cannabis use patterns.

Insula gray matter volume (GMV): average drinks/drinking day

Family history group by insula GMV interaction on average drinks/drinking day

− 2.3

1.2

0.03

Model summary

F_(5,41) = 2.9, p = 0.02, R² = 0.3

FH+: average drinks/drinking day

2.8

1.3

0.02

Model summary

F_(3,16) = 10.9, p = 0.0007, R² = 0.7

FH−: average drinks/drinking day

0.4

2.1

0.7

Model summary

F_(3,24) = 0.3, p = 0.8, R² = 0.04

Insula gray matter volume (GMV): maximum number of cannabis use days/weeks

Maximum number of cannabis use days/week

− 3.3

0.8

0.01

Model summary

F_(3,12) = 5.1, p = 0.02, R² = 0.6