Figure 2
Lect2 KO mice attenuate diet-induced inflammation in the liver. (A) Graph shows bodyweight of Lect2 KO and wild-type mice fed an HFHS diet. 8 week-old-male mice were fed an HF diet for 4 weeks (n = 7–10). The graph shows the liver triglyceride content of Lect2 KO and wild-type mice fed an HF diet. 8 week-old-male mice were fed an HF diet for 4 weeks (n = 7–10). Blood levels of LECT2 from Lect2 KO and wild-type mice following fasting for 12 h. 8 week-old-male mice were fed HF diet for 4 weeks. (B) Hematoxylin and eosin staining of liver from Lect2 KO and wild-type mice fed an HF diet. 8 week-old-male mice were fed an HF diet for 4 weeks (n = 7–10). (C) Graphs show mRNA levels of genes involved in inflammation and lipid metabolism in the liver of Lect2 KO and wild-type mice fed an HF diet. 8 week-old-male mice were fed an HF diet for 4 weeks. *P < 0.05.
