Table 1 The detail clinical features and the results of univariate and multivariable Cox regression analyses in training cohort.
From: Development of an immune-related gene pairs index for the prognosis analysis of metastatic melanoma
Level | Number (%) | Univariate cox analysis | Multivariate cox analysis | |
|---|---|---|---|---|
p Value | HR (95%CI) | p Value | ||
Age | ||||
< 60 | 202 (57.1) | 3.15e−15* | 10.09 (20.93–4.86) | 5.5e−10* |
≥ 60 | 152 (42.9) | |||
Gender | ||||
Male | 224 (63.3) | 2.74e−04* | 1.49 (2.13–1.04) | 0.03* |
Female | 130 (36.7) | |||
T stage | ||||
T0 | 23 (6.5) | 0.271 | 1.01 (1.46–0.69) | 0.97 |
T1 | 40 (11.3) | |||
T2 | 71 (20.1) | |||
T3 | 80 (22.6) | |||
T4 | 68 (19.2) | |||
Tis | 7 (2.0) | |||
TX | 42 (11.9) | |||
NA | 23 (6.5) | |||
N stage | ||||
N0 | 171 (48.3) | 0.036* | 1 (1.15–0.88) | 0.97 |
N1 | 65 (18.4) | |||
N2 | 39 (11.0) | |||
N3 | 45 (12.7) | |||
NX | 18 (5.1) | |||
NA | 16 (4.5) | |||
M stage | ||||
M0 | 313 (88.4) | 0.005* | 1.17 (1.37–0.99) | 0.06 |
M1 | 19 (5.4) | |||
NA | 22 (6.2) | |||
Stage | ||||
I | 74 (20.9) | 0.359 | 1.26 (3.04–0.52) | 0.61 |
II | 59 (16.7) | |||
III | 143 (40.4) | |||
IV | 18 (5.1) | |||
NA | 60 (16.9) | |||
Radiation therapy | ||||
NO | 264 (74.6) | 5.42e−04* | 1.25 (1.64–0.95) | 0.11 |
YES | 72 (20.3) | |||
NA | 18 (5.1) | |||
Disease free survival | ||||
NO TUMOR | 132 (37.3) | 0.003* | 1.07 (1.61–0.71) | 0.76 |
TUMOR | 215 (60.7) | |||
NA | 7 (2.0) | |||
IRGPI | ||||
High IRGPI | 192 (54.2) | 0.714 | 2.32 (3.4–1.58) | 1.9e−05* |
Low IRGPI | 162 (45.8) | |||
OS status | ||||
Dead | 186 (52.5) | – | – | – |
Alive | 168 (47.5) | |||
