Table 2 The information of 24 IRGPs in the selected model.

From: Development of an immune-related gene pairs index for the prognosis analysis of metastatic melanoma

IRG 1

Full name

IRG 2

Full name

Coefficient

CREB1

cAMP responsive element binding protein 1

TNFSF13B

Tumor necrosis factor superfamily member 13b

0.022

HLA-DOB

Major histocompatibility complex, class II, DO beta

CETP

Cholesteryl ester transfer protein

− 0.083

HLA-DQA1

Major histocompatibility complex, class II, DQ alpha 1

C3

Complement C3

− 0.061

HLA-DQA1

Major histocompatibility complex, class II, DQ alpha 1

NR2F6

Nuclear receptor subfamily 2 group F member 6

− 0.025

CXCL14

C-X-C motif chemokine ligand 14

CMTM8

CKLF like MARVEL transmembrane domain containing 8

0.029

CXCL11

C-X-C motif chemokine ligand 11

FABP7

Fatty acid binding protein 7

− 0.033

CXCL11

C-X-C motif chemokine ligand 11

TUBB3

Tubulin beta 3 class III

− 0.079

CXCL13

C-X-C motif chemokine ligand 13

SHC4

SHC adaptor protein 4

− 0.001

CCL13

C–C motif chemokine ligand 13

FABP4

Fatty acid binding protein 4

− 0.063

CCL8

C–C motif chemokine ligand 8

TUBB3

Tubulin beta 3 class III

− 0.51

SLC22A17

Solute carrier family 22 members 17

GNAI1

G protein subunit alpha i1

− 0.295

NOX4

NADPH oxidase 4

PRKCB

Protein kinase C beta

− 0.173

IDO1

Indoleamine 2,3-dioxygenase 1

CXCR3

C-X-C motif chemokine receptor 3

− 0.014

TNFSF10

Tumor necrosis factor superfamily member 10

PGF

Placental growth factor

− 0.094

IRF1

Interferon regulatory factor 1

PPP3CB

Protein phosphatase 3 catalytic subunit beta

− 0.009

ZYX

Zyxin

GPI

Glucose-6-phosphate isomerase

− 0.097

ITGAV

Integrin subunit alpha V

PIK3CD

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

− 0.049

ABCC4

ATP binding cassette subfamily C member 4

VEGFC

Vascular endothelial growth factor C

− 0.006

CDH1

Cadherin 1

IL6ST

Interleukin 6 signal transducer

0.139

CD72

CD72 molecule

NR2F1

Nuclear receptor subfamily 2 group F member 1

− 0.122

SEMA3B

Semaphorin 3B

NR2F2

Nuclear receptor subfamily 2 group F member 2

− 0.133

SEMA3C

Semaphorin 3C

MET

MET proto-oncogene, receptor tyrosine kinase

− 0.136

TNC

Tenascin C

SORT1

Sortilin 1

− 0.096

DKK1

Dickkopf WNT signaling pathway inhibitor 1

ITK

IL2 inducible T-cell kinase

0.07

  1. Abbreviation: IRGPs immune related gene pairs, IRG1 immune related gene 1, IRG2 immune related gene 2.