Table 1 Demographic characteristics and retinal neuronal layer thickness of the participants.

From: Changes in retinal microvasculature and retinal layer thickness in association with apolipoprotein E genotype in Alzheimer’s disease

 

MCI (n = 40)

Controls (n = 37)

p-value

Age, mean ± SD, years

72.8 ± 8.6

69.0 ± 10.4

0.15

Sex (M/F), (n/n)

25/15

17/20

0.17

DM (n)

3

6

0.30

HTN (n)

9

14

0.21

OD/OS (n/n)

20/20

19/18

 > 0.999

SE, mean ± SD, Diopter

−0.48 ± 2.1

−0.45 ± 1.8

0.84

VA, mean ± SD, logMAR

0.03 ± 0.05

0.04 ± 1.8

0.28

Retinal neuronal layer thickness, mean ± SD, μm

Total retina

315.1 ± 14.2

314.9 ± 14.4

0.87

RNFL

20.0 ± 2.4

19.9 ± 2.5

0.95

GCL

39.1 ± 3.8

38.3 ± 6.3

0.92

IPL

34.6 ± 2.1

33.9 ± 3.6

0.47

INL

37.2 ± 3.9

36.1 ± 3.3

0.20

OPL

33.7 ± 4.7

33.5 ± 5.1

0.83

ONL

67.5 ± 9.9

68.3 ± 8.5

0.96

RPE

15.3 ± 1.7

16.0 ± 1.9

0.25

  1. MCI = mild cognitive impairment, M = male, F = female, DM = diabetes mellitus, HTN = hypertension, SE = spherical equivalent, OD = right eye, OS = left eye, VA = visual acuity, logMAR = logarithm of the minimum angle of resolution, RNFL = retinal nerve fiber layer, GCL = ganglion cell layer, IPL = inner plexiform layer, INL = inner nuclear layer, OPL = outer plexiform layer, ONL = outer nuclear layer, RPE = retinal pigment epithelium, SD = standard deviation.
  2. *p < 0.05.
Back to article page