Figure 3
VASH1 protein transfer restores erectile function in diabetic mice. (a) Representative intracavernous (ICP) responses for the age-matched control and streptozotocin-induced diabetic mice stimulated at 2 weeks after repeated intracavernous injections of PBS (days − 3 and 0) or VASH1 protein (days − 3 and 0; 1 μg/20 μL or 4 μg/20 μL). The stimulus interval is indicated by a solid bar. (b,c) Ratios of mean maximal ICP and total ICP (area under the curve) to mean systolic blood pressure (MSBP) calculated for each group. Each bar depicts the mean (± SE) values from N = 6 animals per group. **P < 0.01 and ***P < 0.001 vs. control group. #P < 0.05 and ##P < 0.01 vs. PBS-treated DM group. DM diabetes mellitus.
