Figure 4
VASH1 protein transfer restores cavernous endothelial cell and pericyte content in diabetic mice. (a) PECAM-1 (red) and NG2 (green) staining in cavernous tissue from age-matched control and streptozotocin-induced diabetic mice 2 weeks after receiving repeated intracavernous injections of PBS (days − 3 and 0) or VASH1 protein (days − 3 and 0; 4 μg/20 μL). Scale bar = 100 µm. (b,c) Quantification of cavernous endothelial cell and pericyte content by Image J. Each bar depicts the mean (± SE) values from N = 6 animals per group. *P < 0.05, **P < 0.01 vs. control group. #P < 0.05, ###P < 0.001 vs. PBS-treated DM group. DM diabetes mellitus.
