Figure 2 | Scientific Reports

Figure 2

From: Novel HLA-B7-restricted human metapneumovirus epitopes enhance viral clearance in mice and are recognized by human CD8+ T cells

Figure 2

HMPV-specific TCD8 identified with fluorescently labeled HLA tetramer molecules in B7tg mice. B7tg mice were infected i.n. with 1 × 106 PFU HMPV and lungs (A) and spleens (B) collected on day 10 post-infection. Live/dead dye and fluorescently labeled CD8 and CD3 antibodies were used to identify live CD8+ T lymphocytes and fluorescently labeled HMPV-specific tetramers, as well as an irrelevant vaccinia virus (A34R) tetramer, were used to identify HMPV epitope-specific TCD8.

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