Figure 2 | Scientific Reports

Figure 2

From: Point mutations in Candida glabrata 3-hydroxy-3-methylglutaryl-coenzyme A reductase (CgHMGR) decrease enzymatic activity and substrate/inhibitor affinity

Figure 2

The phylogenetic tree of the catalytic domain of HMGR enzymes in different organisms. The percentage of replicated trees in which the associated taxa are grouped in the 100 bootstrap replicates is shown next to the branches. The phylogenetic tree is drawn to scale, with the length of the branches representing the corresponding evolutionary distances according to the MEGA6 program, the maximum likelihood method, and the WAG + G model. The development of the species in the clade that encompasses Candida glabrata (in red) was based on whole genome duplication (WGD). In the clade containing Candida albicans (in green), the species developed based on genetic code transition (GCT).

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