Figure 1

The maximum rate of increase in D-dimer levels (D–Drate, panel (A,C) and maximum D-dimer concentrations (D–Dmax, panel B,D) measured during plasma clot lysis in the permeation assay in patients without arterial thromboembolism (ATE) (n = 289) and patients with subsequent ATE including (n = 21, panel A,B) and excluding (n = 16, panel C,D) patients with recurrent VTE (n = 5).