Table 1 List of metabolites in PKO against HFD.

From: Untargeted serum metabolites profiling in high-fat diet mice supplemented with enhanced palm tocotrienol-rich fraction using UHPLC-MS

Metabolite

Fold-change (log2)a

p value

Xanthine

8.4072

0.032212

Isovaltrate

7.5962

0.000106

Limonin

5.3958

0.001841

(15Z)-9,12,13-Trihydroxy-15-octadecenoic acid

1.7977

0.0164

Sphinganine

1.2211

0.00767

Xanthosine

1.1539

0.040012

Spermidine

1.0461

0.049502

N-Methylhistamine

0.924

0.027424

13,14-Dihydro PGF2a

0.91792

0.0459

Taurochenodeoxycholic acid

0.8734

0.029087

D-Sphingosine

0.81567

0.043147

Nicotinamide

0.80644

0.047193

L-Glutamic acid

0.79069

0.038329

indospicine

0.77237

0.007492

Dehydrofelodipine

 − 0.60594

0.034791

3-Ethoxyandrosta-3,5-dien-17beta-ol propanoate

 − 0.82539

0.047198

Dihydrolipoate

 − 0.94479

0.003521

6-Methoxyquinoline

 − 0.98664

0.013298

D-Glucurono-6,2-lactone

 − 1.0511

0.034869

Nicotine glucuronide

 − 1.0877

0.008214

3-Indoxyl sulphate

 − 1.0989

0.009656

Netilmicin

 − 1.2984

0.038169

Sulfoglycolithocholic acid

 − 1.5375

0.020523

Cholic acid

 − 1.6234

0.025529

Cyclic-3,20-bis(1,2-ethanediyl acetal)-11alpha-(acetyloxy)-5alpha,6alpha-epoxypregnane-3,20-dione

 − 1.7427

0.006786

Oleamide

 − 1.9727

0.041883

Hexanoylcarnitine

 − 2.2494

0.01046

C16 Sphinganine

 − 2.2925

0.002023

2-amino-hexadecanoic acid

 − 3.1642

0.000117

Phytosphingosine

 − 4.2454

0.000344

gamma-Glutamylcysteine

 − 5.4559

2.20 × 10−7

N-Undecanoylglycine

 − 6.0083

2.25 × 106

Deoxyadenosine monophosphate

 − 7.0388

3.23 × 10−6

  1. aFold change values described are the ratio of PKO/HFD. The values are arranged from highest ratio (up-regulated) to the lowest (down-regulated).
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