Table 2 List of metabolites in TRF against HFD.

From: Untargeted serum metabolites profiling in high-fat diet mice supplemented with enhanced palm tocotrienol-rich fraction using UHPLC-MS

Metabolite

Fold-change (log2)a

p value

Isovaltrate

7.6429

0.00149

( +)-abscisic acid beta-D-glucopyranosyl ester

5.9806

7.22E−05

Paucin

5.1866

4.45E−06

2,2-dichloro-1,1-ethanediol

4.0956

0.045523

Mupirocin

3.8462

0.030777

Taurochenodeoxycholic acid

3.8371

0.019658

L-Olivosyl-oleandolide

3.7225

0.030254

Taurohyocholic acid

3.6062

0.019682

Taurocholic acid

3.2801

0.023508

Ouabain

2.9975

0.02805

pseudaminic acid

1.8028

0.006537

(15Z)-9,12,13-Trihydroxy-15-octadecenoic acid

1.5964

0.005335

indospicine

1.286

0.000424

N-Acetyl-ala-ala-ala-methylester

1.0483

0.009132

3-propylmalic acid

0.86307

0.008511

Palmitoyl sphingomyelin

0.62613

0.041855

Trigonelline

0.59162

0.029791

Glycerophosphocholine

 − 0.59431

0.029666

11-amino-undecanoic acid

 − 0.60037

0.0468

Z-Arg-Arg-NHMec; Benzyloxycarbonylarginyl-arginine 4-methylcoumarin-7-ylamide

 − 0.62836

0.035491

Artocarpin

 − 0.68462

0.008561

lysophosphatidylethanolamine 0:0/20:4(8Z,11Z,14Z,17Z)

 − 0.70745

1.69E−05

Biotin sulfone

 − 0.73369

0.029679

C16 Sphingosine-1-phosphate

 − 0.74896

0.021534

Glycerophospho-N-Oleoyl Ethanolamine

 − 0.81377

0.000621

1-octadecylglycero-3-phosphocholine

 − 0.82645

0.046111

4-Pyridoxic acid

 − 0.86159

0.007487

Arachidonic acid

 − 0.87795

0.030662

2-Hydroxy-4-methylthiobutanoic acid

 − 0.88465

0.020117

DL-Lysine

 − 0.88836

0.000675

Allantoic acid

 − 0.89861

0.000472

Istamycin C1

 − 1.1599

0.010525

D-Sphingosine

 − 1.3232

0.001413

O-6-deoxy-a-L-galactopyranosyl-(1- > 3)-O-b-D-galactopyranosyl-(1- > 3)-O-2-(acetylamino)-2-deoxy-b-D-glucopyranosyl-[1- > 3(or 1- > 6)]-O-[O-b-D-galactopyranosyl-(1- > 4)-2-(acetylamino)-2-deoxy-b-D-glucopyranosyl-[1- > 6(or 1- > 3)]]-O-b-D-galactopyranosyl-(1- > 4)-D-G

 − 1.3292

0.016392

Oleamide

 − 1.3343

0.038229

Netilmicin

 − 1.3959

0.001809

3-Phenyllactic acid

 − 1.4653

0.011921

N-(5Z,8Z,11Z,14Z-docosatetraenoyl)-ethanolamine

 − 1.4942

0.003432

Hexadecanamide

 − 1.6835

0.025216

C16 Sphinganine

 − 2.4489

9.82E−06

2-amino-hexadecanoic acid

 − 2.7841

2.10 × 10−6

Phytosphingosine

 − 4.9224

6.48 × 10−8

N-Undecanoylglycine

 − 6.1852

1.11 × 10−9

  1. aFold change values described are the ratio of TRF/HFD. The values are arranged from highest ratio (up-regulated) to the lowest (down-regulated).
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