Table 3 List of metabolites in ETRF against HFD.

From: Untargeted serum metabolites profiling in high-fat diet mice supplemented with enhanced palm tocotrienol-rich fraction using UHPLC-MS

Metabolite

Fold-change (log2)a

p value

Xanthine

9.2854

0.014729

( +)-abscisic acid beta-D-glucopyranosyl ester

7.239

4.26E−14

Paucin

5.5155

8.23E−10

Hypoxanthine

4.2737

0.023667

Urocanic acid

1.0146

0.003096

L-Ascorbic acid 2-sulfate

0.81939

0.042157

3-Isopropylmalic acid

0.66469

0.029228

6-Methylnicotinamide

0.6507

0.023537

Trigonelline

0.64591

0.003216

PE(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)

 − 0.59609

0.00128

Indolelactic acid

 − 0.61605

0.003202

Ethylenediaminetetraacetic acid (EDTA)

 − 0.61975

0.014081

LysoPE(0:0/18:2(9Z,12Z))

 − 0.62167

0.017277

PC(20:4(5Z,8Z,11Z,14Z)/0:0)

 − 0.65119

0.014296

L-Threonine

 − 0.66945

0.003803

6′-[(carboxymethyl)-C-hydroxycarbonimidoyl]-2′,3′,4,4′,5,6-hexahydroxy-[1,1′-biphenyl]-2-carboxylic acid

 − 0.68279

0.016133

C16 Sphinganine

 − 0.70745

1.69E−05

LysoPE(0:0/20:4(5Z,8Z,11Z,14Z))

 − 0.70745

1.69E−05

Butenylcarnitine

 − 0.71444

0.034775

3-Indoxyl sulphate

 − 0.73989

0.029273

Pyridoxamine

 − 0.76347

0.003376

Arachidonic acid

 − 0.76829

0.002173

DL-ß-Leucine

 − 0.7949

0.01281

C16 Sphingosine-1-phosphate

 − 0.80979

0.002821

(9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoic acid

 − 0.8574

0.004992

L-Acetylcarnitine

 − 0.86237

0.011089

LysoPE(18:1(9Z)/0:0)

 − 0.88265

5.92E−06

DL-Lysine

 − 0.88836

0.000675

Allantoic acid

 − 0.89861

0.000472

4-Pyridoxic acid

 − 0.98191

0.001064

Sphinganine

 − 1.0196

0.015898

3-Ethoxyandrosta-3,5-dien-17beta-ol propanoate

 − 1.0514

0.049831

N-(5Z,8Z,11Z,14Z-docosatetraenoyl)-ethanolamine

 − 1.0554

0.007735

Netilmicin

 − 1.1707

0.01109

Cyclic-3,20-bis(1,2-ethanediyl acetal)-11alpha-(acetyloxy)-5alpha,6alpha-epoxypregnane-3,20-dione

 − 1.317

0.025216

D-Sphingosine

 − 1.3232

0.001413

Cholic acid

 − 1.486

0.029476

3-Phenyllactic acid

 − 1.5077

0.0071

2-amino-hexadecanoic acid

 − 2.7841

2.10 × 10−6

Phytosphingosine

 − 4.9224

6.48 × 10−8

  1. aFold change values described are the ratio of ETRF/HFD. The values are arranged from highest ratio (up-regulated) to the lowest (down-regulated).
Back to article page