Table 2 Significant prognostic factors for cancer specific survival of metastatic urothelial carcinoma patients treated with pembrolizumab identified by Cox regression analysis with stepwise regression analysis in discovery cohort (n = 165).

From: FAN score comprising fibrosis-4 index, albumin–bilirubin score and neutrophil–lymphocyte ratio is a prognostic marker of urothelial carcinoma patients treated with pembrolizumab

 

Univariate

Multivariate

HR

95% CI

p-value

HR

95%CI

p-value

Lower

Higher

Lower

Higher

Fib-4 index (≥ 3.5 vs. < 3.5)

2.08

1.18

3.66

0.011

2.13

1.20

3.76

0.010

ALBI score (> − 2.6 vs. ≤ − 2.6)

2.24

1.51

3.33

 < 0.001

1.91

1.27

2.88

0.002

NLR (≥ 5.0 vs. < 5.0)

2.14

1.44

3.19

 < 0.001

1.84

1.22

2.79

0.004

  1. Fib-4 index: fibrosis-4 index, ALBI score: albumin–bilirubin score, NLR: neutrophil–lymphocyte ratio, HR: hazard ratio, CI: confidence interval.
Back to article page