Table 3 The association between change in LA features and worsening categories of left ventricular diastolic dysfunction.

From: Comparing left atrial indices by CMR in association with left ventricular diastolic dysfunction and adverse clinical outcomes

Left atrial measurement

Diastolic Dysfunction category

ORADJ* (95% CL)

ORADJ**(95% CL)

LA strain (reservoir) (%)

Normal

Reference

Reference

I

1.11 (1.03, 1.19)

1.05 (0.96, 1.14)

II

1.25 (1.14, 1.38)

1.20 (1.07, 1.34)

III

1.50 (1.30, 1.73)

1.38 (1.17, 1.63)

LA strain (conduit) (%)

Normal

Reference

Reference

I

1.05 (0.97, 1.14)

1.01 (0.90, 1.12)

II

1.06 (0.97, 1.16)

1.01 (0.90, 1.13)

III

1.24 (1.08, 1.42)

1.18 (0.99, 1.41)

LA strain (booster pump) (%)

Normal

Reference

Reference

I

1.20 (1.08, 1.35)

1.15 (0.99, 1.34)

II

1.47 (1.27, 1.70)

1.43 (1.19, 1.71)

III

1.64 (1.35, 1.97)

1.48 (1.19, 1.85)

LAVmin (ml/m2)

Normal

Reference

Reference

I

1.31 (1.13, 1.50)

1.33 (1.10, 1.61)

II

1.37 (1.19, 1.58)

1.40 (1.16, 1.70)

III

1.40 (1.21, 1.62)

1.43 (1.18, 1.73)

LAVmax (ml/m2)

Normal

Reference

Reference

I

1.08 (1.03, 1.13)

1.13 (1.04, 1.23)

II

1.12 (1.07, 1.17)

1.17 (1.08, 1.28)

III

1.14 (1.08, 1.20)

1.19 (1.09, 1.30)

LAEF (%)

Normal

Reference

Reference

I

1.16 (1.07, 1.24)

1.14 (1.04, 1.25)

II

1.20 (1.11, 1.30)

1.19 (1.08, 1.31)

III

1.24 (1.14, 1.35)

1.21 (1.09, 1.34)

LV longitudinal strain (%)

Normal

Reference

N/A

I

1.61 (1.28, 2.03)

II

1.66 (1.31, 2.11)

III

1.99 (1.49, 2.65)

  1. ORADJ = adjusted odds ratio; 95% CL = 95% confidence limit; LAVmax = left atrial maximum volume; LAVmin = left atrial minimum volume; LAEF = left atrial emptying fraction.
  2. *Adjusted for age, gender, BSA (except in models with LAVmax and LAVmin), diabetes, hypertension, and smoking.
  3. **Additionally adjusted for left ventricular global longitudinal strain.