Table 3 Overall and subgroup exercise effects on MQ derived from neuromuscular outcomes in older adults.
From: Exercise effects on muscle quality in older adults: a systematic review and meta-analysis
Main effects | n | Sample size | SMD (95% CI) | I2 | P-value |
|---|---|---|---|---|---|
Overall effect | 14 | 538 | 0.59 (0.33 to 0.85) | 51% | < 0.001 |
Without outlier | 13 | 482 | 0.49 (0.29 to 0.69) | 11% | < 0.001 |
Risk of bias | |||||
Low risk of bias† | 1 | 24 | 0.30 (− 1.11 to 0.51) | – | – |
Some concerns or high risk of bias | 13 | 514 | 0.64 (0.39 to 0.89) | 45% | < 0.001 |
Population | |||||
Physically healthy | 10 | 367 | 0.43 (0.21 to 0.64) | 0% | < 0.001 |
Overweight/ Obese | 2 | 73 | 0.79 (− 0.10 to 1.68) | 67% | 0.082 |
Moderate functional capacity† | 1 | 42 | 0.72 (0.10 to 1.35) | – | – |
Sarcopenic obesity† | 1 | 56 | 1.69 (1.07 to 2.32) | – | – |
Intervention delivery | |||||
Supervised | 13 | 492 | 0.61 (0.33 to 0.89) | 54% | < 0.001 |
Unsupervised | – | – | − | – | – |
Intervention modality | |||||
Resistance exercise | 10 | 353 | 0.64 (0.27 to 1.01) | 63% | < 0.001 |
Resistance exercise + nutrition† | 1 | 28 | 0.44 (− 0.32 to 1.20) | – | – |
Aerobic exercise† | 1 | 22 | 0.19 (− 0.65 to 1.03) | – | – |
Aerobic exercise + nutrition† | 1 | 21 | 0.57 (− 0.31 to 1.45) | – | – |
Combined resistance and aerobic exercise† | 1 | 49 | 0.33 (− 0.24 to 0.91) | – | – |
Combined resistance and aerobic exercise + caloric restriction† | 1 | 46 | 0.38 (− 0.21 to 0.97) | – | – |
Multimodal exercise program† | 1 | 42 | 0.72 (0.10 to 1.35) | – | – |
Assessment methods—knee extensors | |||||
1-RM/DXA | 3 | 111 | 0.65 (0.26 to 1.05) | 0% | 0.001 |
1-RM/CT† | 1 | 27 | 1.30 (0.45 to 2.14) | – | – |
1-RM/US† | 1 | 36 | 0.07 (− 0.58 to 0.72) | – | – |
Isokinetic/DXA | 5 | 195 | 0.48 (0.19 to 0.78) | 0% | 0.001 |
Isokinetic/CT | 2 | 91 | 0.42 (− 0.16 to 0.99) | 46% | 0.155 |
Isometric/DXA† | 1 | 56 | 1.69 (1.07 to 2.32) | – | – |
Isometric/CT† | 1 | 49 | 0.30 (− 0.27 to 0.87) | – | – |
Isometric/BIA† | 1 | 36 | 0.09 (− 0.58 to 0.76) | – | – |
Assessment methods—plantar flexors | |||||
30° sec−1/US† | 1 | 24 | − 0.46 (− 1.27 to 0.35) | – | – |
Isometric/US† | 1 | 24 | 0.00 (− 0.80 to 0.80) | – | – |