Figure 5 | Scientific Reports

Figure 5

From: Deficiency of lung-specific claudin-18 leads to aggravated infection with Cryptococcus deneoformans through dysregulation of the microenvironment in lungs

Figure 5

Effects of luCldn-18 deficiency on ion concentration and pH in BALFs. (a) The concentrations of several ions (Na+, Cl−, K+) and pH were measured in BALFs of uninfected luCldn-18+/+ (n = 3) and luCldn-18−/− mice (n = 3). Each column represents the mean ± SD. (b) luCldn-18+/+ (n = 4) and luCldn-18−/− mice (n = 4) were infected intratracheally with C. deneoformans. pH in BALFs was measured on day 3 and 7 post-infection. Each column represents the mean ± SD. *, p < 0.05. NS, not significant. There were no mice excluded from this analysis.

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