Table 1 Baseline clinical characteristics of the patients.
From: Cardiovascular morbidities in postoperative colorectal cancer patients
Study population (N = 2875) | Patients with new-onset CVD (n = 141) | Patients without new-onset CVD (n = 2734) | p | |
|---|---|---|---|---|
Age, median (IQR) | 62.0 (IQR, 54.0–70.0) | 70.0 (IQR, 61.0–75.0) | 61.0 (IQR, 53.0–70.0) | < 0.001 |
Age > 65 years, n (%) | 1138 (39.6) | 90 (63.8) | 1048 (38.3) | < 0.001 |
Sex, male (%) | 1727 (60.1) | 104 (73.8) | 1623 (59.4%) | 0.001 |
BMI, median (IQR) | 23.5 (IQR, 21.5–25.55) | 24.0 (IQR, 21.85–25.8) | 23.5 (21.5–25.5) | 0.572 |
Hypertension, n (%) | 1094 (38.1) | 85 (60.3) | 1009 (36.9) | < 0.001 |
Diabetes mellitus, n (%) | 512 (17.8) | 59 (41.8) | 453 (16.6) | < 0.001 |
Hyperlipidemia, n (%) | 269 (9.4) | 11 (7.8) | 258 (9.4) | 0.656 |
Coronary arterial disease, n (%) | 120 (4.2) | 49 (34.8) | 71 (2.6) | < 0.001 |
Pulmonary disease, n (%) | 141 (4.9) | 8 (5.7) | 133 (4.9) | 0.687 |
Ischemic stroke, n (%) | 61 (2.1) | 11 (7.8) | 50 (1.8) | < 0.001 |
Valvular heart disease, n (%) | 701 (24.4) | 39 (27.6) | 662 (24.2) | 0.366 |
Atrial fibrillation, n (%) | 31 (1.1) | 5 (3.5) | 26 (1.0) | 0.016 |
Chronic kidney disease, n (%) | 59 (2.1) | 12 (8.5) | 47 (1.7) | < 0.001 |
ASA, n (%) | ||||
1 | 934 (32.5) | 10 (7.1) | 924 (33.8) | < 0.001 |
2 | 1794 (62.4) | 76 (53.9) | 1718 (62.8) | |
3 | 126 (4.4) | 46 (32.6) | 80 (2.9) | |
4 | 21 (0.7) | 9 (6.4) | 12 (0.4) | |
ECOG, n (%) | ||||
1 | 2659 (92.5) | 102 (72.3) | 2557 (93.5) | < 0.001 |
2 | 206 (7.2) | 34 (24.1) | 172 (6.3) | |
3 | 8 (0.3) | 3 (2.1) | 5 (0.2) | |
4 | 2 (0.1) | 2 (14) | 0 | |
Smoking, n (%) | ||||
Current smoker | 247 (8.6) | 19 (13.5) | 228 (8.3) | 0.003 |
Ex-smoker | 1006 (35.0) | 56 (39.7) | 950 (34.7) | |
Alcohol, n (%) | ||||
Current drinker | 515 (17.9) | 33 (23.6) | 482 (17.6) | 0.247 |
Ex-drinker | 936 (32.6) | 40 (28.6) | 896 (32.8) | |
Total cholesterol, mean (SD) | 153.09 (35.0) | 141.3 (37.7) | 153.7 (34.8) | < 0.001 |
CRP, mean (SD) | 0.48 (1.64) | 0.68 (1.79) | 0.46 (1.60) | 0.190 |
