Figure 5
From: Selective and predicable amine conjugation sites by kinetic characterization under excess reagents

In vitro cancer cell killing activity of ADCs using SK-BR-3 cells. The IC50 values of ADC1 (open circle) and ADC2 (diamond) were 1.9 and 0.7 nM, respectively, against > 66.7 nM (square) for the control determined based on the data (mean ± SEM, n ≥ 2).