Figure 1

An example region of interest (ROI) analysis of the sciatic nerve in a 20-year-old female Charcot-Marie-Tooth disease type IA patient. Axial fat fraction maps of the 3D multiple gradient echo Dixon-based MRI (AāC) where the ROI analyses of the sciatic nerve were performed: hamstring tendon origin ((A), level 1), lesser trochanter of the femur ((B), level 2), and gluteus maximus tendon insertion ((C), level 3). The ROIs are indicated on the fat fraction maps showing the measured cross-sectional area and fat fraction values for the sciatic nerve. An illustration (D) shows the three levels where image analyses were performed.